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Biochemistry Primer for Exercise Science-4th Edition

Biochemistry Primer for Exercise Science-4th Edition

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    Students trained in traditional exercise physiology have learned the basic concepts of energy but often don’t fully understand human energy consumption at the molecular level. Biochemistry Primer for Exercise Science, Fourth Edition, provides an introduction to biochemistry that will give readers greater insight into the molecular aspects of human physical activity.

    Reflecting the rapid development of the field, this classic text continues to present the essentials of biochemistry—molecular biology, basic chemistry, metabolism, and transcription regulation—in an easy-to-understand format. The fourth edition features the most recent research in exercise biochemistry plus new and revised content, including the following:

    • All-new coverage of the control of biochemistry and biochemical and muscular adaptations to exercise and training via signaling pathways, an area of study that has received much attention in recent years

    • Added information on the regulation of gene expression, which highlights the need for students to comprehend the basics of molecular biology

    • Next Stage sections in each chapter, which lead students toward emerging areas of knowledge in the field by examining new or controversial areas of research

    • An integration of the chapters on DNA, RNA, and the regulation of protein synthesis to provide a more focused and effective presentation of these key concepts


    Biochemistry Primer for Exercise Science, Fourth Edition, combines information from nutrition, physiology, and biochemistry to provide a clear explanation of the working of metabolism and the human body’s response to physical activity. Special elements throughout the text help to demystify this complex and dynamic field of study. Key points reinforce essential concepts and aid readers in relating them to sport and exercise. Chapter summaries outline important information to take away, and review questions with answers allow readers to test their knowledge of each chapter’s content. A comprehensive glossary and the list of abbreviations found on the inside front and back covers help readers become familiar with commonly used biochemistry terms, and a reference list provides a starting point for exploring areas of interest in more detail.  

    With its combination of essential topics, new findings, and future directions in research, Biochemistry Primer for Exercise Science, Fourth Edition, is a perfect resource for anyone looking to build an understanding of exercise biochemistry. Both students and professionals alike will find the information they need to begin their exploration of this fascinating field of study.

    Audience

    A supplementary course text for upper-undergraduate and graduate students in exercise physiology, exercise biochemistry, and sport nutrition; a reference for professionals in those fields.

    Table of Contents

    Preface
    Acknowledgments
    Tribute to Michael E. Houston

    Part I: Proteins and Enzymes: The Basis of Biochemistry
    Chapter 1: Amino Acids, Peptides, and Proteins
    Nature of Amino Acids
    Characteristics of Peptides
    Structure of Proteins
    Next Stage: Proteomics
    Summary
    Review Questions

    Chapter 2: Enzymes
    Enzymes as Catalysts
    Rates of Enzymatic Reactions
    Enzyme Cofactors
    Classification of Enzymes
    Protein Transporters
    Oxidations and Reductions
    Regulation of Enzyme Activity
    Measurement of Enzyme Activity
    Next Stage: Redox Regulation of the SERCA Pump in Vascular Physiology and Disease
    Summary
    Review Questions

    Chapter 3: Gene Transcription and Protein Synthesis
    DNA and RNA
    Transcription
    Posttranscriptional Modifications of RNA
    Translation
    Posttranslational Processing of Polypeptides
    Protein Degradation
    Regulation of Gene Expression in Exercise and Training
    Next Stage: MicroRNAs and the Adaptive Response to Exercise Training
    Summary
    Review Questions

    Part II: Metabolism: Regulation and Adaptation to Exercise and Training
    Chapter 4: Energy Systems and Bioenergetics
    Energy Requirements of Skeletal Muscle
    Energy-Rich Phosphates
    Energy Systems
    Bioenergetics
    Next Stage: Epigenetic Control of Skeletal Muscle Fiber Type and Metabolic Potential
    Summary
    Review Questions

    Chapter 5: Oxidative Phosphorylation
    Overview of Metabolism
    Mitochondria
    Citric Acid Cycle
    Electron Transport Chain
    Coupled Phosphorylation
    Regulation of Oxidative Phosphorylation
    Quantification of Redox Reactions
    Oxidants and Antioxidants
    Next Stage: Effects of Aging and Exercise Training on Muscle Mitochondria
    Summary
    Review Questions

    Chapter 6: Carbohydrate and Related Metabolism
    Carbohydrates
    Cellular Uptake of Glucose
    Phosphorylation of Glucose
    Glycolysis
    Glycogen Metabolism
    Lactate Metabolism
    Oxidation of Cytoplasmic NADH
    Gluconeogenesis
    Pentose Phosphate Pathway
    Signaling Pathways
    Next Stage: Carbohydrate, Exercise Performance, and Fatigue
    Summary
    Review Questions

    Chapter 7: Lipid Metabolism
    Types of Lipids
    Fat Storage and Metabolism
    Oxidation of Fatty Acids
    Oxidation of Ketone Bodies
    Synthesis of Fatty Acids
    Fat as Fuel for Exercise
    Metabolism During Exercise: Fat Versus Carbohydrate
    Adipose Tissue as an Endocrine Tissue
    Cholesterol
    Next Stage: Exercise, 24-Hour Fat Oxidation, and Weight Loss
    Summary
    Review Questions

    Chapter 8: Amino Acid and Protein Metabolism
    Overview of Amino Acid Metabolism
    Degradation of Amino Acids
    Urea Cycle
    Fate of Amino Acid Carbon Skeletons
    Amino Acid Metabolism During Exercise
    Additional Roles for Amino Acids
    Next Stage: Effects of Diet and Exercise on Protein Degradation and Synthesis
    Summary
    Review Questions

    Appendix: Answers to Review Questions
    Glossary
    References
    Index
    About the Authors

    Reviews

    "This welcome update of the previous edition includes the most recent peer-reviewed literature that examines exercise science in conjunction with the basic sciences. The authors are well-respected scientists in the field and their expertise, in combination with the updated literature, results in a current and trusted information source for this area.”

    --Doody’s Book Review (5-star review)